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3011 Coelenterazine-SOL in vivo说明

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3011 Coelenterazine-SOL in vivo说明
Nanolight®Technology是一家生物技术公司,开发天然,发光海洋蛋白或海洋生物发光的广泛应用。 Nanolight部门致力于成为制药,农业和研究产品行业新产品开发的高价值试剂和报告系统的先驱。

有价值的生命科学用于Nanolight®的技术包括高通量药物发现,功能基因组学,肿瘤成像,放射性同位素替代和分子诊断

3011 Coelenterazine-SOL in vivo说明

 

苏州蚂蚁淘生物科技秒速牛牛官网是Nanolight品牌特约代理商,提供Nanolight所有产品,质量保证,货号型号齐

 

Nanolight®Technology是一家生物技术公司,开发天然,发光海洋蛋白或海洋生物发光的广泛应用。 Nanolight部门致力于成为制药,农业和研究产品行业新产品开发的高价值试剂和报告系统的先驱。

有价值的生命科学用于Nanolight®的技术包括高通量药物发现,功能基因组学,肿瘤成像,放射性同位素替代和分子诊断


Nanolight品牌3011 Coelenterazine-SOL in vivo中英文说明书

 

3011 Coelenterazine-SOL in vivo说明

 

Cat # 3031 Coelenterazine-SOL in vivo

Native Coelenterazine formulated to be water-soluble and safe for in vivo imaging applications with Gaussia Luciferase.

 

Coelenterazine is often dissolved in Propyleneglycol (PG) in combination with other alcohols for in vivo imaging studies. Large intravenous doses of PG given over a short period of time can be toxic, including  hyperosmolality, increased anion gap metabolic acidosis (due to lactic acidosis), acute kidney injury, and sepsis-like syndrome.


This can be avoided using water-soluble Coelenterazine. It is formulated to be isosmotic and easily secreted by the kidneys. Thus save for repeated i.v. injections. Water-soluble Coelenterazine can be injected up to a 500 µg/100 µl concentration, achieving very high Coelenterazine levels within the body and leADIng to high Gaussia luciferase signals.

 

Content:native Coelenterazine + non-toxic additives for water-solublity
Packaging size:500 ug CTZ / vial in a freeze-dried form
Storage:

 
sealed vials can be stored at:
-80°C for long-term storage
-20°C for short-term storage    Store dry and dark!
Application:just add sterile water, vortex and use up to 500 ug CTZ in a single injection 
Application example:




















 

              

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

A detailed describtion of this new  water soluble Coelenterazine can be found in:

 

A Water-Soluble Coelenterazine for Sensitive In Vivo Imaging of Coelenterate Luciferases. Danielle Morse and Bakhos A Tannous
Molecular Therapy 20, 692-693 (April 2012) | doi:10.1038/mt.2012.38

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